Can I Run DeepSeek V4.1 on AMD Ryzen AI Max+ 395?

Name: LLM Configurator — GPU VRAM Checker
Author: LLM Configurator

Written by Jakub Rusinowski · Last updated August 15, 2026

No. DeepSeek V4.1 needs 966.0 GB at Q4 (experimental, datacenter only) and the AMD Ryzen AI Max+ 395 has only 96 GB. No quantization we publish closes a gap that size.

The numbers

Model	DeepSeek V4.1
Parameters	1.6T (49B active)
Quantization	Q4 (experimental, datacenter only)
VRAM needed	966.0 GB
AMD Ryzen AI Max+ 395 VRAM	96 GB
Verdict	Does not fit

What to do next

Step down to a smaller size in this family — no single consumer card we track fits this one.

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Running DeepSeek V4.1 on this card:

Ryzen AI Max+ 395 Laptop (Strix Halo, up to 128GB)

96 GB VRAM · 120 W board power

2026 prices are volatile — check the current listing.

Check price on Amazon

Other DeepSeek V4.1 sizes on the AMD Ryzen AI Max+ 395

DeepSeek V4.1 Flash — runs at a lower quant (171.5 GB)

DeepSeek V4.1 on nearby hardware

NVIDIA H100 80GB (80 GB) — does not fit
Apple M4 Max (128 GB) — does not fit

All DeepSeek V4.1 sizes on the AMD Ryzen AI Max+ 395 | VRAM calculator for DeepSeek V4.1 | AMD Ryzen AI Max+ 395 GPU page | Check your hardware