Autor: Jakub Rusinowski · Ostatnia aktualizacja: 15 sierpnia 2026
Yes. Nemotron Cascade 2 70B needs 42.3 GB at Q4_K_M and the AMD Ryzen AI Max+ 395 has 96 GB, leaving about 53.7 GB of headroom, at roughly 4 tok/s (estimated) with room for up to 128K of context.
| Model | Nemotron Cascade 2 70B |
| Parameters | 70B |
| Quantization | Q4_K_M |
| VRAM needed | 42.3 GB |
| AMD Ryzen AI Max+ 395 VRAM | 96 GB |
| Verdict | Runs |
| Max context | 128K |
| Estimated speed | ~4 tok/s |
Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.
Running Nemotron Cascade 2 70B on this card:
At 2 hrs/day, buying (~$1,999) beats renting at $0.77/hr after about 3.6 years.
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.
All Nemotron Cascade 2 sizes on the AMD Ryzen AI Max+ 395 | VRAM calculator for Nemotron Cascade 2 70B | AMD Ryzen AI Max+ 395 GPU page | Check your hardware