Can I Run Cosmos 3 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Written by Jakub Rusinowski · Last updated July 21, 2026

Yes — comfortably

Yes, comfortably — Cosmos 3 Super at Q8_0 needs about 71.1 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB), leaving ~56.9 GB spare and running at ~5.4 tok/s (estimated), with room for about 16,384 tokens of context.

Confidence: medium · Recommended quantization: Q8_0 · Estimated speed: ~5.4 tok/s

Framework Desktop (Ryzen AI Max+ 395, 128 GB) — what it gives a model

Usable memory for models128 GB
Memory bandwidth256 GB/s
Form factorMini PC
Operating systemWindows or Linux
Memory upgradeableNo — soldered

Cosmos 3 on Framework Desktop (Ryzen AI Max+ 395, 128 GB): memory by quantization

QuantMemory neededFits 128 GB?Max contextEst. speedDownload
F16131.1 GB✗ No128 GB
Q8_071.1 GB✓ Yes16K~5.4 tok/s68 GB
Q6_K55.6 GB✓ Yes16K~6.9 tok/s52.5 GB
Q5_K_M48.5 GB✓ Yes16K~7.9 tok/s45.4 GB
Q4_K_M41.8 GB✓ Yes16K~9.2 tok/s38.6 GB
Q3_K_M30.4 GB✓ Yes16K~12.6 tok/s27.3 GB
Q2_K24.2 GB✓ Yes16K~15.9 tok/s21 GB

Which Cosmos 3 sizes fit

VariantNeeds at Q4_K_MFits?Est. speed
Cosmos 3 Super41.8 GB✓ Fits~9.2 tok/s
Cosmos 3 Nano11.9 GB✓ Fits~32.1 tok/s
Cosmos 3 Edge4.1 GB✓ Fits~91.8 tok/s

What to watch out for

Framework Desktop 128 GB limitations

Recommended setup

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

How these numbers are calculated

FAQ

Can I run Cosmos 3 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Yes, comfortably — Cosmos 3 Super at Q8_0 needs about 71.1 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB), leaving ~56.9 GB spare and running at ~5.4 tok/s (estimated), with room for about 16,384 tokens of context.

Which quantization of Cosmos 3 should I use on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Q8_0 — it needs about 71.1 GB of the 128 GB available, downloads as roughly 68 GB, and runs at an estimated 5.4 tokens/sec with up to 16K of context.

What limits Cosmos 3 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Nothing binding — the model fits with headroom and generates at a usable speed on this hardware.

Which runtime should I use?

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

Other Computers

Other Models on Framework Desktop (Ryzen AI Max+ 395, 128 GB)

Cosmos 3 on GPUs

What This Model Is Good At

Model & Tools

← Can I Run It? | Cosmos 3 model page | Check your hardware