Can I Run DeepSeek V4-Pro on NVIDIA H100 80GB (PCIe)?

Written by Jakub Rusinowski · Last updated July 21, 2026

No. DeepSeek V4-Pro needs 527.4 GB at 8K context (526 GB weights + 1.4 GB KV cache/overhead) at Q2 (experimental, datacenter only) and the NVIDIA H100 80GB (PCIe) has only 80 GB. No quantization we publish closes a gap that size.

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The numbers

ModelDeepSeek V4-Pro
Parameters1.6T (49B active)
QuantizationQ2 (experimental, datacenter only)
VRAM needed (8K context)527.4 GB
NVIDIA H100 80GB (PCIe) VRAM80 GB
VerdictDoes not fit

DeepSeek V4-Pro on the NVIDIA H100 80GB (PCIe): VRAM by quantization

QuantVRAM neededFits 80 GB?Max contextWhole PC
F163201.4 GB✗ No——
Q8_01701.4 GB✗ No——
Q6_K1313.4 GB✗ No——
Q5_K_M1135.4 GB✗ No——
Q4_K_M967.4 GB✗ No——
Q3_K_M683.4 GB✗ No——
Q2_K527.4 GB✗ No——

Assumes an 8K-token context with an f16 KV cache, on an estimated architecture — this model publishes no config we can read. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 80 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Context costs VRAM too. At Q2 (experimental, datacenter only) on the NVIDIA H100 80GB (PCIe): 8K 527.4 GB ✗ · 32K 529.1 GB ✗ · 128K 536 GB ✗. Past 8K it no longer fits 80 GB — a q8_0 KV cache buys roughly half of that back, which the calculator will price for you.

What to do next

Step down to a smaller size in this family — no single consumer card we track fits this one.

No compatible GPU? DeepSeek V4 on 128 GB of system RAM, CPU only: runs, but it is tight.

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Running DeepSeek V4-Pro on this card:

NVIDIA H100 80GB PCIe
80 GB VRAM · 350 W board power
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Won't fit — rent DeepSeek V4-Pro instead

DeepSeek V4-Pro needs ~527 GB but this GPU has 80 GB. Rent a 8× H100 (640 GB)-class GPU by the hour instead of buying one:

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RunPod $23.12/hr
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other DeepSeek V4 sizes on the NVIDIA H100 80GB (PCIe)

DeepSeek V4-Pro on nearby hardware

All DeepSeek V4 sizes on the NVIDIA H100 80GB (PCIe) | DeepSeek V4-Pro model page | NVIDIA H100 80GB (PCIe) GPU page | VRAM calculator | Check your hardware