Can I Run Gemma 3 12B Instruct on NVIDIA GeForce RTX 5090?

Written by Jakub Rusinowski · Last updated September 29, 2026

Yes. Gemma 3 12B Instruct needs 11.1 GB at 8K context (7.2 GB weights + 3.9 GB KV cache/overhead) at Q4_K_M and the NVIDIA GeForce RTX 5090 has 32 GB, leaving about 20.9 GB of headroom, at roughly 125 tok/s (estimated) with room for up to 32K of context.

See what else this hardware can run →

The numbers

ModelGemma 3 12B Instruct
Parameters12B
QuantizationQ4_K_M
VRAM needed (8K context)11.1 GB
NVIDIA GeForce RTX 5090 VRAM32 GB
VerdictRuns
Max context32K
Estimated speed~125 tok/s

Gemma 3 12B Instruct on the NVIDIA GeForce RTX 5090: VRAM by quantization

QuantVRAM neededFits 32 GB?Max contextWhole PC
F1627.9 GB✓ Yes16K—
Q8_016.6 GB✓ Yes32KBuild for this
Q6_K13.7 GB✓ Yes32K—
Q5_K_M12.4 GB✓ Yes32KBuild for this
Q4_K_M11.1 GB✓ Yes32KBuild for this
Q3_K_M9 GB✓ Yes64K—
Q2_K7.8 GB✓ Yes64K—

Assumes an 8K-token context with an f16 KV cache. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 32 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Context costs VRAM too. At Q4_K_M on the NVIDIA GeForce RTX 5090: 8K 11.1 GB · 32K 20.4 GB · 128K 57.4 GB ✗. Past 128K it no longer fits 32 GB — a q8_0 KV cache buys roughly half of that back, which the calculator will price for you.

What to do next

Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.

No compatible GPU? Gemma 3 12B Instruct on 16 GB of system RAM, CPU only: runs, but it is tight.

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Running Gemma 3 12B Instruct on this card:

NVIDIA GeForce RTX 5090 32GB
32 GB VRAM · 575 W board power
2026 prices are volatile — check the current listing.
Check price on Amazon

Buy vs. rent Gemma 3 12B Instruct
Buy the GPU
~$1,999
NVIDIA GeForce RTX 5090 · MSRP
Rent by the hour
from $0.34/hr
RTX 4090 (24 GB) class

At 2 hrs/day, buying (~$1,999) beats renting at $0.34/hr after about 8.2 years.

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RunPod $0.34/hr
Rent on RunPod →
Vast.ai $0.35/hr · typical low · varies
Rent on Vast.ai →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Gemma 3 sizes on the NVIDIA GeForce RTX 5090

Gemma 3 12B Instruct on nearby hardware

All Gemma 3 sizes on the NVIDIA GeForce RTX 5090 | Gemma 3 12B Instruct model page | NVIDIA GeForce RTX 5090 GPU page | VRAM calculator | Check your hardware