Can I Run Gemma 3n on RTX 4090 Desktop (24 GB VRAM, 64 GB RAM)?

Written by Jakub Rusinowski · Last updated April 1, 2025

Yes — comfortably

Yes, comfortably — Gemma 3n E4B at Q8_0 needs about 10.3 GB of the 24 GB usable on RTX 4090 Desktop (24 GB VRAM, 64 GB RAM), leaving ~13.7 GB spare and running at ~118.3 tok/s (estimated), with room for about 32,768 tokens of context.

Confidence: medium · Recommended quantization: Q8_0 · Estimated speed: ~118.3 tok/s

RTX 4090 Desktop (24 GB VRAM, 64 GB RAM) — what it gives a model

Usable memory for models24 GB
Memory bandwidth1008 GB/s
Form factorDesktop
Operating systemWindows or Linux
Memory upgradeableYes

Gemma 3n on RTX 4090 Desktop (24 GB VRAM, 64 GB RAM): memory by quantization

QuantMemory neededFits 24 GB?Max contextEst. speedDownload
F1617.6 GB✓ Yes32K~75.4 tok/s15.7 GB
Q8_010.3 GB✓ Yes32K~118.3 tok/s8.3 GB
Q6_K8.4 GB✓ Yes32K~138.7 tok/s6.4 GB
Q5_K_M7.5 GB✓ Yes32K~150.6 tok/s5.6 GB
Q4_K_M6.7 GB✓ Yes32K~164 tok/s4.7 GB
Q3_K_M5.3 GB✓ Yes32K~192.7 tok/s3.3 GB
Q2_K4.5 GB✓ Yes32K~213.3 tok/s2.6 GB

Which Gemma 3n sizes fit

VariantNeeds at Q4_K_MFits?Est. speed
Gemma 3n E4B6.7 GB✓ Fits~164 tok/s
Gemma 3n E2B5.1 GB✓ Fits~225.4 tok/s

What to watch out for

RTX 4090 desktop limitations

Recommended setup

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

How these numbers are calculated

FAQ

Can I run Gemma 3n on RTX 4090 Desktop (24 GB VRAM, 64 GB RAM)?

Yes, comfortably — Gemma 3n E4B at Q8_0 needs about 10.3 GB of the 24 GB usable on RTX 4090 Desktop (24 GB VRAM, 64 GB RAM), leaving ~13.7 GB spare and running at ~118.3 tok/s (estimated), with room for about 32,768 tokens of context.

Which quantization of Gemma 3n should I use on RTX 4090 Desktop (24 GB VRAM, 64 GB RAM)?

Q8_0 — it needs about 10.3 GB of the 24 GB available, downloads as roughly 8.3 GB, and runs at an estimated 118.3 tokens/sec with up to 32K of context.

What limits Gemma 3n on RTX 4090 Desktop (24 GB VRAM, 64 GB RAM)?

Nothing binding — the model fits with headroom and generates at a usable speed on this hardware.

Which runtime should I use?

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

Other Computers

Other Models on RTX 4090 Desktop (24 GB VRAM, 64 GB RAM)

Gemma 3n on GPUs

What This Model Is Good At

Model & Tools

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