Written by Jakub Rusinowski · Last updated August 15, 2026
Yes. Gemma 4 E4B needs 4.5 GB at Q4 (QAT) and the NVIDIA GeForce RTX 4090 has 24 GB, leaving about 19.5 GB of headroom, at roughly 130 tok/s (estimated) with room for up to 64K of context.
| Model | Gemma 4 E4B |
| Parameters | 4B (Efficient) |
| Quantization | Q4 (QAT) |
| VRAM needed | 4.5 GB |
| NVIDIA GeForce RTX 4090 VRAM | 24 GB |
| Verdict | Runs |
| Max context | 64K |
| Estimated speed | ~130 tok/s |
Nothing to change — run it at Q4 (QAT). If you want more capability, check whether the next size up also fits.
Running Gemma 4 E4B on this card:
At 2 hrs/day, buying (~$1,599) beats renting at $0.34/hr after about 6.5 years.
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.
All Gemma 4 sizes on the NVIDIA GeForce RTX 4090 | VRAM calculator for Gemma 4 E4B | NVIDIA GeForce RTX 4090 GPU page | Check your hardware