Can I Run GLM-5 / GLM-5.1 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Written by Jakub Rusinowski · Last updated May 1, 2026

Yes — comfortably

Yes, comfortably — GLM-5.1 72B at Q3_K_M needs about 33.9 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB), leaving ~94.1 GB spare and running at ~5.9 tok/s (estimated), with room for about 65,536 tokens of context.

Confidence: medium · Recommended quantization: Q3_K_M · Estimated speed: ~5.9 tok/s

Framework Desktop (Ryzen AI Max+ 395, 128 GB) — what it gives a model

Usable memory for models128 GB
Memory bandwidth256 GB/s
Form factorMini PC
Operating systemWindows or Linux
Memory upgradeableNo — soldered

GLM-5 / GLM-5.1 on Framework Desktop (Ryzen AI Max+ 395, 128 GB): memory by quantization

QuantMemory neededFits 128 GB?Max contextEst. speedDownload
F16147.2 GB✗ No144 GB
Q8_079.7 GB✓ Yes64K~2.5 tok/s76.5 GB
Q6_K62.3 GB✓ Yes64K~3.2 tok/s59 GB
Q5_K_M54.2 GB✓ Yes64K~3.6 tok/s51 GB
Q4_K_M46.7 GB✓ Yes64K~4.3 tok/s43.5 GB
Q3_K_M33.9 GB✓ Yes64K~5.9 tok/s30.7 GB
Q2_K26.9 GB✓ Yes64K~7.6 tok/s23.7 GB

Which GLM-5 / GLM-5.1 sizes fit

VariantNeeds at Q4_K_MFits?Est. speed
GLM-5 744B455.2 GB✗ Too large
GLM-5.1 72B46.7 GB✓ Fits~4.3 tok/s
GLM-5 32B22 GB✓ Fits~9.3 tok/s
GLM-5 9B7.4 GB✓ Fits~29.7 tok/s

What to watch out for

Framework Desktop 128 GB limitations

Recommended setup

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

How these numbers are calculated

FAQ

Can I run GLM-5 / GLM-5.1 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Yes, comfortably — GLM-5.1 72B at Q3_K_M needs about 33.9 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB), leaving ~94.1 GB spare and running at ~5.9 tok/s (estimated), with room for about 65,536 tokens of context.

Which quantization of GLM-5 / GLM-5.1 should I use on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Q3_K_M — it needs about 33.9 GB of the 128 GB available, downloads as roughly 30.7 GB, and runs at an estimated 5.9 tokens/sec with up to 64K of context.

What limits GLM-5 / GLM-5.1 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Nothing binding — the model fits with headroom and generates at a usable speed on this hardware.

Which runtime should I use?

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

Other Computers

Other Models on Framework Desktop (Ryzen AI Max+ 395, 128 GB)

GLM-5 / GLM-5.1 on GPUs

What This Model Is Good At

Model & Tools

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