Can I Run MiMo-V2.5 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?
Written by Jakub Rusinowski · Last updated September 6, 2026
Yes
Yes — MiMo-V2.5 310B at Q2_K needs about 106.6 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB) (~21.4 GB spare), at ~26.3 tok/s (estimated), with room for about 32,768 tokens of context.
Confidence: medium · Recommended quantization: Q2_K · Estimated speed: ~26.3 tok/s
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Framework Desktop (Ryzen AI Max+ 395, 128 GB) — what it gives a model
| Usable memory for models | 128 GB |
| Memory bandwidth | 256 GB/s |
| Form factor | Mini PC |
| Operating system | Windows or Linux |
| Memory upgradeable | No — soldered |
MiMo-V2.5 on Framework Desktop (Ryzen AI Max+ 395, 128 GB): memory by quantization
| Quant | Memory needed | Fits 128 GB? | Max context | Est. speed | Download |
|---|
| F16 | 624.7 GB | ✗ No | — | — | 620 GB |
| Q8_0 | 334.1 GB | ✗ No | — | — | 329.4 GB |
| Q6_K | 258.9 GB | ✗ No | — | — | 254.2 GB |
| Q5_K_M | 224.4 GB | ✗ No | — | — | 219.7 GB |
| Q4_K_M | 191.9 GB | ✗ No | — | — | 187.2 GB |
| Q3_K_M | 136.8 GB | ✗ No | — | — | 132.1 GB |
| Q2_K | 106.6 GB | ✓ Yes | 32K | ~26.3 tok/s | 101.9 GB |
Which MiMo-V2.5 sizes fit
| Variant | Needs at Q4_K_M | Fits? | Est. speed |
|---|
| MiMo-V2.5-Pro 1T | 610.3 GB | ✗ Too large | — |
| MiMo-V2.5 310B | 191.9 GB | ✗ Too large | — |
What to watch out for
- Q2_K is the only quantization that fits, and it is a heavily degraded one — expect noticeably worse output than the same model at Q4_K_M. A smaller model at Q4 is usually the better trade.
- 2 larger variants of MiMo-V2.5 do not fit and would need CPU offload or different hardware.
- This model does not publish its full attention configuration, so the KV-cache share of these figures is inferred from its parameter count rather than computed exactly.
- Memory on this machine is not upgradeable, so the configuration you buy is the ceiling for every model you will ever run on it.
Framework Desktop 128 GB limitations
- Memory is soldered LPDDR5X — unusually for Framework, this is the one component that cannot be upgraded.
- ROCm/Vulkan support for Strix Halo is younger than CUDA; check your runtime supports it before buying.
Recommended setup
Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving
How these numbers are calculated
- Memory need = quantized weights + KV cache at 8,192 tokens (f16) + 0.8 GB runtime overhead.
- 128 GB unified memory at 256 GB/s, shared between CPU and GPU.
- Throughput is a memory-bandwidth roofline estimate, not a measurement. It is labelled "estimated" everywhere it appears.
- KV cache is inferred from the parameter count because this model does not publish its full attention configuration.
FAQ
Can I run MiMo-V2.5 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?
Yes — MiMo-V2.5 310B at Q2_K needs about 106.6 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB) (~21.4 GB spare), at ~26.3 tok/s (estimated), with room for about 32,768 tokens of context.
Which quantization of MiMo-V2.5 should I use on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?
Q2_K — it needs about 106.6 GB of the 128 GB available, downloads as roughly 101.9 GB, and runs at an estimated 26.3 tokens/sec with up to 32K of context.
What limits MiMo-V2.5 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?
Nothing binding — the model fits with headroom and generates at a usable speed on this hardware.
Which runtime should I use?
Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving
Other Models on Framework Desktop (Ryzen AI Max+ 395, 128 GB)
MiMo-V2.5 on GPUs
What This Model Is Good At
Model & Tools
← Can I Run It? | MiMo-V2.5 model page | Check your hardware