Can I Run Nemotron 3 Super on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Written by Jakub Rusinowski · Last updated August 15, 2026

Yes

Yes — Nemotron 3 Super 120B-A12B at Q6_K needs about 102.1 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB) (~25.9 GB spare), at ~16.4 tok/s (estimated), with room for about 65,536 tokens of context.

Confidence: medium · Recommended quantization: Q6_K · Estimated speed: ~16.4 tok/s

Framework Desktop (Ryzen AI Max+ 395, 128 GB) — what it gives a model

Usable memory for models128 GB
Memory bandwidth256 GB/s
Form factorMini PC
Operating systemWindows or Linux
Memory upgradeableNo — soldered

Nemotron 3 Super on Framework Desktop (Ryzen AI Max+ 395, 128 GB): memory by quantization

QuantMemory neededFits 128 GB?Max contextEst. speedDownload
F16243.7 GB✗ No240 GB
Q8_0131.2 GB✗ No127.5 GB
Q6_K102.1 GB✓ Yes64K~16.4 tok/s98.4 GB
Q5_K_M88.7 GB✓ Yes64K~18.5 tok/s85.1 GB
Q4_K_M76.1 GB✓ Yes128K~21.1 tok/s72.5 GB
Q3_K_M54.8 GB✓ Yes128K~27.5 tok/s51.2 GB
Q2_K43.1 GB✓ Yes128K~33.1 tok/s39.4 GB

What to watch out for

Framework Desktop 128 GB limitations

Recommended setup

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

How these numbers are calculated

FAQ

Can I run Nemotron 3 Super on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Yes — Nemotron 3 Super 120B-A12B at Q6_K needs about 102.1 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB) (~25.9 GB spare), at ~16.4 tok/s (estimated), with room for about 65,536 tokens of context.

Which quantization of Nemotron 3 Super should I use on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Q6_K — it needs about 102.1 GB of the 128 GB available, downloads as roughly 98.4 GB, and runs at an estimated 16.4 tokens/sec with up to 64K of context.

What limits Nemotron 3 Super on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Nothing binding — the model fits with headroom and generates at a usable speed on this hardware.

Which runtime should I use?

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

Other Computers

Other Models on Framework Desktop (Ryzen AI Max+ 395, 128 GB)

Nemotron 3 Super on GPUs

What This Model Is Good At

Model & Tools

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