Can I Run Nemotron Cascade 2 on NVIDIA L40S?

Written by Jakub Rusinowski · Last updated July 21, 2026

Yes, comfortably — you'll have ~5.7 GB of headroom running Nemotron Cascade 2 70B at Q4_K_M (42.2625 GB, ~18 tok/s (est.)) with room for up to 16K context.

Buy This HardwareNVIDIA L40S 48GB — 48 GB VRAM · 350 W board powerDeploy in the Cloud NowNVIDIA L40S on RunPod — from $0.86/hr · rate checked 2026-08

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NVIDIA L40S 48GB
48 GB VRAM · 350 W board power
2026 prices are volatile — check the current listing.
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NVIDIA L40S Specs

VRAM48 GB
Memory Bandwidth864 GB/s

Nemotron Cascade 2 70B on the NVIDIA L40S: VRAM by quantization

QuantVRAM neededFits 48 GB?Max context
F16142 GB✗ No
Q8_076.4 GB✗ No
Q6_K59.4 GB✗ No
Q5_K_M51.6 GB✗ No
Q4_K_M44.3 GB✓ Yes16K
Q3_K_M31.8 GB✓ Yes32K
Q2_K25 GB✓ Yes64K

VRAM needed assumes a 4K-token context with an f16 KV cache; “Max context” is the largest window that still fits in 48 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Nemotron Cascade 2 Sizes That Fit the NVIDIA L40S

Nemotron Cascade 2 70BQ4_K_M · 42.2625 GB · ~18 tok/s (est.)
Nemotron Cascade 2 30BQ4_K_M · 18.1125 GB · ~39 tok/s (est.)
Buy vs. rent Nemotron Cascade 2
Buy the GPU
~$7,499
NVIDIA L40S · MSRP
Rent by the hour
from $0.77/hr
A100 (80 GB) class

At 2 hrs/day, buying (~$7,499) beats renting at $0.77/hr after about 13.5 years.

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Vast.ai $0.77/hr · typical low · varies
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RunPod $1.39/hr
Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Is the NVIDIA L40S enough to run Nemotron Cascade 2 locally?

Yes, comfortably — you'll have ~5.7 GB of headroom running Nemotron Cascade 2 70B at Q4_K_M (42.2625 GB, ~18 tok/s (est.)) with room for up to 16K context.

What's the best Nemotron Cascade 2 size for the NVIDIA L40S?

Nemotron Cascade 2 70B at Q4_K_M quantization (42.2625 GB), estimated ~18 tokens/sec, up to 16K context.

Nemotron Cascade 2 on Other GPUs

Popular Models on the NVIDIA L40S

VRAM Tier

Troubleshooting

Buying Guide

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