Can I Run Nemotron Cascade 2 on NVIDIA L40S?

Written by Jakub Rusinowski · Last updated September 11, 2026

Yes, but it's tight — Nemotron Cascade 2 70B at Q4_K_M needs 45.4 GB at 8K context (42.3 GB weights + 3.1 GB KV cache/overhead), leaving ~2.6 GB of the NVIDIA L40S's 48 GB, at ~18 tok/s (est.), with room for up to 16K context.

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NVIDIA L40S 48GB
48 GB VRAM · 350 W board power
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NVIDIA L40S Specs

VRAM48 GB
Memory Bandwidth864 GB/s

Nemotron Cascade 2 70B on the NVIDIA L40S: VRAM by quantization

QuantVRAM neededFits 48 GB?Max contextWhole PC
F16143.2 GB✗ No——
Q8_077.6 GB✗ No——
Q6_K60.6 GB✗ No——
Q5_K_M52.8 GB✗ No——
Q4_K_M45.4 GB✓ Yes16K—
Q3_K_M33 GB✓ Yes32K—
Q2_K26.2 GB✓ Yes64K—

Assumes an 8K-token context with an f16 KV cache, on an estimated architecture — this model publishes no config we can read. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 48 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Context costs VRAM too. At Q4_K_M on the NVIDIA L40S: 8K 45.4 GB · 32K 52.6 GB ✗ · 125K 80.3 GB ✗. Past 32K it no longer fits 48 GB — a q8_0 KV cache buys roughly half of that back, which the calculator will price for you.

No compatible GPU? Nemotron Cascade 2 on 24 GB of system RAM, CPU only: runs.

Nemotron Cascade 2 Sizes That Fit the NVIDIA L40S (at 8K context)

Nemotron Cascade 2 70BQ4_K_M · 45.4 GB at 8K context · ~18 tok/s (est.)
Nemotron-Cascade 2 30B-A3BQ4_K_M · 21.7 GB at 8K context · ~166 tok/s (est.)
Buy vs. rent Nemotron Cascade 2
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~$7,499
NVIDIA L40S · MSRP
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from $0.77/hr
A100 (80 GB) class

At 2 hrs/day, buying (~$7,499) beats renting at $0.77/hr after about 13.5 years.

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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Is the NVIDIA L40S enough to run Nemotron Cascade 2 locally?

Yes, but it's tight — Nemotron Cascade 2 70B at Q4_K_M needs 45.4 GB at 8K context (42.3 GB weights + 3.1 GB KV cache/overhead), leaving ~2.6 GB of the NVIDIA L40S's 48 GB, at ~18 tok/s (est.), with room for up to 16K context.

What's the best Nemotron Cascade 2 size for the NVIDIA L40S?

Nemotron Cascade 2 70B at Q4_K_M quantization needs 45.4 GB at 8K context (42.3 GB weights + 3.1 GB KV cache/overhead), estimated ~18 tokens/sec, up to 16K context.

Nemotron Cascade 2 on Other GPUs

Popular Models on the NVIDIA L40S

VRAM Tier

Troubleshooting

Buying Guide

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