Can I Run Qwen 2.5 72B Instruct on Apple M1?

Name: LLM Configurator — GPU VRAM Checker
Author: LLM Configurator

Written by Jakub Rusinowski · Last updated August 15, 2026

No. Qwen 2.5 72B Instruct needs 43.5 GB at Q4_K_M and the Apple M1 has only 16 GB. No quantization we publish closes a gap that size.

The numbers

Model	Qwen 2.5 72B Instruct
Parameters	72B
Quantization	Q4_K_M
VRAM needed	43.5 GB
Apple M1 VRAM	16 GB
Verdict	Does not fit

What to do next

Either step down to a smaller size in this family, or move to a NVIDIA RTX 6000 Ada Generation (48 GB), the cheapest card we track with enough VRAM.

Affiliate disclosure: Some links on this page are affiliate links — if you buy through them, LLM Configurator may earn a commission at no extra cost to you. As an Amazon Associate, LLM Configurator earns from qualifying purchases.

Cheapest card we track with enough VRAM for Qwen 2.5 72B Instruct:

NVIDIA RTX 6000 Ada Generation 48GB

48 GB VRAM · 300 W board power

2026 prices are volatile — check the current listing.

Check price on Amazon

Won't fit — rent Qwen 2.5 72B Instruct instead

Qwen 2.5 72B Instruct needs ~43 GB but this GPU has 16 GB. Rent a A100 (80 GB)-class GPU by the hour instead of buying one:

Affiliate links — we may earn a commission if you sign up, at no extra cost to you.

Vast.ai $0.77/hr · typical low · varies

Rent on Vast.ai →

RunPod $1.39/hr

Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Qwen 2.5 Family sizes on the Apple M1

Qwen 2.5 Coder 32B — runs at a lower quant (19.3 GB)
Qwen 2.5 14B Instruct — runs (8.5 GB)
Qwen 2.5 7B Instruct — runs (4.6 GB)

Qwen 2.5 72B Instruct on nearby hardware

Intel Arc B580 (12 GB) — does not fit
AMD Radeon RX 7900 XT (20 GB) — does not fit

All Qwen 2.5 Family sizes on the Apple M1 | VRAM calculator for Qwen 2.5 72B Instruct | Apple M1 GPU page | Check your hardware