Written by Jakub Rusinowski · Last updated July 21, 2026
Yes, comfortably — you'll have ~36.5 GB of headroom running Qwen 2.5 72B Instruct at Q4_K_M (43.47 GB, ~35 tok/s (est.)) with room for up to 64K context.
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| VRAM | 80 GB |
| Memory Bandwidth | 2000 GB/s |
| Quant | VRAM needed | Fits 80 GB? | Max context |
|---|---|---|---|
| F16 | 146.1 GB | ✗ No | — |
| Q8_0 | 78.6 GB | ✓ Yes | 8K |
| Q6_K | 61.2 GB | ✓ Yes | 32K |
| Q5_K_M | 53.2 GB | ✓ Yes | 64K |
| Q4_K_M | 45.6 GB | ✓ Yes | 64K |
| Q3_K_M | 32.8 GB | ✓ Yes | 128K |
| Q2_K | 25.8 GB | ✓ Yes | 128K |
VRAM needed assumes a 4K-token context with an f16 KV cache; “Max context” is the largest window that still fits in 80 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.
| Qwen 2.5 72B Instruct | Q4_K_M · 43.47 GB · ~35 tok/s (est.) |
| Qwen 2.5 Coder 32B | Q4_K_M · 19.32 GB · ~70 tok/s (est.) |
| Qwen 2.5 14B Instruct | Q4_K_M · 8.4525 GB · ~130 tok/s (est.) |
| Qwen 2.5 7B Instruct | Q4_K_M · 4.5885 GB · ~197 tok/s (est.) |
At 2 hrs/day, buying (~$25,000) beats renting at $0.77/hr after about 45.1 years.
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.
Yes, comfortably — you'll have ~36.5 GB of headroom running Qwen 2.5 72B Instruct at Q4_K_M (43.47 GB, ~35 tok/s (est.)) with room for up to 64K context.
Qwen 2.5 72B Instruct at Q4_K_M quantization (43.47 GB), estimated ~35 tokens/sec, up to 64K context.
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