Can I Run Qwen 2.5 Family on NVIDIA GeForce RTX 4080?

Written by Jakub Rusinowski · Last updated July 12, 2026

Yes, comfortably — Qwen 2.5 14B Instruct at Q4_K_M needs 10.9 GB at 8K context (8.5 GB weights + 2.4 GB KV cache/overhead), leaving ~5.1 GB of the NVIDIA GeForce RTX 4080's 16 GB, at ~62 tok/s (est.), with room for up to 32K context.

See what else this hardware can run →

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NVIDIA GeForce RTX 4080 16GB
16 GB VRAM · 320 W board power
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NVIDIA GeForce RTX 4080 Specs

VRAM16 GB
Memory Bandwidth717 GB/s

Qwen 2.5 14B Instruct on the NVIDIA GeForce RTX 4080: VRAM by quantization

QuantVRAM neededFits 16 GB?Max contextWhole PC
F1630.4 GB✗ No——
Q8_017.3 GB✗ No——
Q6_K13.9 GB✓ Yes16K—
Q5_K_M12.3 GB✓ Yes16K—
Q4_K_M10.9 GB✓ Yes32K—
Q3_K_M8.4 GB✓ Yes32K—
Q2_K7 GB✓ Yes32K—

Assumes an 8K-token context with an f16 KV cache. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 16 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Superseded model. Qwen 2.5 Family has been superseded by Qwen 3. This page is kept for reference; the newer family is a better starting point. Can I run Qwen 3 on NVIDIA GeForce RTX 4080? →

Context costs VRAM too. At Q4_K_M on the NVIDIA GeForce RTX 4080: 8K 10.9 GB · 32K 15.7 GB · 128K 35 GB ✗. Past 128K it no longer fits 16 GB — a q8_0 KV cache buys roughly half of that back, which the calculator will price for you.

No compatible GPU? Qwen 2.5 14B Instruct on 16 GB of system RAM, CPU only: runs, but it is tight.

Qwen 2.5 Family Sizes That Fit the NVIDIA GeForce RTX 4080 (at 8K context)

Qwen 2.5 14B InstructQ4_K_M · 10.9 GB at 8K context · ~62 tok/s (est.)
Qwen 2.5 7B InstructQ4_K_M · 5.9 GB at 8K context · ~105 tok/s (est.)
Buy vs. rent Qwen 2.5 Family
Buy the GPU
~$1,199
NVIDIA GeForce RTX 4080 · MSRP
Rent by the hour
from $0.34/hr
RTX 4090 (24 GB) class

At 2 hrs/day, buying (~$1,199) beats renting at $0.34/hr after about 4.9 years.

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RunPod $0.34/hr
Rent on RunPod →
Vast.ai $0.35/hr · typical low · varies
Rent on Vast.ai →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Will Qwen 2.5 Family run on the NVIDIA GeForce RTX 4080?

Yes, comfortably — Qwen 2.5 14B Instruct at Q4_K_M needs 10.9 GB at 8K context (8.5 GB weights + 2.4 GB KV cache/overhead), leaving ~5.1 GB of the NVIDIA GeForce RTX 4080's 16 GB, at ~62 tok/s (est.), with room for up to 32K context.

Which Qwen 2.5 Family variant fits best on the NVIDIA GeForce RTX 4080?

Qwen 2.5 14B Instruct at Q4_K_M quantization needs 10.9 GB at 8K context (8.5 GB weights + 2.4 GB KV cache/overhead), estimated ~62 tokens/sec, up to 32K context.

Every Qwen 2.5 Family size on the NVIDIA GeForce RTX 4080

SizeVRAM at 8KVerdictSpeed
Qwen 2.5 72B Instruct47 GBDoes not fit—
Qwen 2.5 Coder 32B22.3 GBRuns at Q2_K—
Qwen 2.5 14B Instruct10.9 GBRuns~62 tok/s
Qwen 2.5 7B Instruct5.9 GBRuns~105 tok/s

Qwen 2.5 Family on Other GPUs

Popular Models on the NVIDIA GeForce RTX 4080

VRAM Tier

Troubleshooting

Buying Guide

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