Written by Jakub Rusinowski · Last updated August 15, 2026
Yes. Qwen 2.5 VL 72B Instruct needs 44.3 GB at Q4_K_M and the Apple M3 Max has 64 GB, leaving about 19.7 GB of headroom, at roughly 5 tok/s (estimated) with room for up to 32K of context.
| Model | Qwen 2.5 VL 72B Instruct |
| Parameters | 72B |
| Quantization | Q4_K_M |
| VRAM needed | 44.3 GB |
| Apple M3 Max VRAM | 64 GB |
| Verdict | Runs |
| Max context | 32K |
| Estimated speed | ~5 tok/s |
Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.
Running Qwen 2.5 VL 72B Instruct on this card:
At 2 hrs/day, buying (~$2,499) beats renting at $0.77/hr after about 4.5 years.
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.
All Qwen 2.5 VL sizes on the Apple M3 Max | VRAM calculator for Qwen 2.5 VL 72B Instruct | Apple M3 Max GPU page | Check your hardware