Can I Run Qwen 3.5 122B-A10B on NVIDIA L40S?

Written by Jakub Rusinowski · Last updated August 15, 2026

Not at Q4_K_M — that needs 73.7 GB and the NVIDIA L40S has 48 GB. Drop to Q2_K and it fits in 43.8 GB, with up to 16K of context.

The numbers

ModelQwen 3.5 122B-A10B
Parameters122B (10B active)
QuantizationQ4_K_M
VRAM needed73.7 GB
NVIDIA L40S VRAM48 GB
VerdictRuns at a lower quant
Fits atQ2_K (43.8 GB)
Max context16K

What to do next

Quantize to Q2_K. That is the cheapest fix — it costs some quality but no money.

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Running Qwen 3.5 122B-A10B on this card:

NVIDIA L40S 48GB
48 GB VRAM · 350 W board power
2026 prices are volatile — check the current listing.
Check price on Amazon

Won't fit — rent Qwen 3.5 122B-A10B instead

Qwen 3.5 122B-A10B needs ~74 GB but this GPU has 48 GB. Rent a A100 (80 GB)-class GPU by the hour instead of buying one:

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Vast.ai $0.77/hr · typical low · varies
Rent on Vast.ai →
RunPod $1.39/hr
Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Qwen 3.5 sizes on the NVIDIA L40S

Qwen 3.5 122B-A10B on nearby hardware

All Qwen 3.5 sizes on the NVIDIA L40S | VRAM calculator for Qwen 3.5 122B-A10B | NVIDIA L40S GPU page | Check your hardware