Mistral Large 3 — local AI model by Mistral AI

Written by Jakub Rusinowski · Last updated

Mistral's open-weight flagship, released 2 December 2025: a 675B MoE with 41B active parameters, Apache-2.0, 256K context. Datacentre-scale to self-host; most readers will rent it.

Variants

The smallest Mistral Large 3 variant needs about 408 GB of VRAM at Q4_K_M — quantized weights plus framework overhead, before any KV cache.

ModelVRAM
Mistral Large 3 675B-A41B →
675B (41B active)
~408.3 GB

Memory is quantized weights plus overhead at Q4_K_M, from the same engine as the GPU & VRAM checker.

How to run Mistral Large 3 locally

Install Ollama, then pull the tag.

ollama run mistral-large-3

Pick a size above for its own VRAM figure, speed estimate and install command.

Licence

Apache-2.0Commercial use permitted

Commercial use permitted. No usage restrictions beyond attribution.

Applies to: Mistral Large 3 675B-A41B

Recommended GPU

The cheapest catalogued GPU that runs Mistral Large 3 locally (min 408 GB VRAM) is the Apple M3 Ultra (512 GB).

Affiliate disclosure: Some links on this page are affiliate links — if you buy through them, LLM Configurator may earn a commission at no extra cost to you. As an Amazon Associate, LLM Configurator earns from qualifying purchases.
Apple Mac Studio M3 Ultra
512 GB VRAM · 60 W board power
2026 prices are volatile — check the current listing.

Can I run Mistral Large 3 on my GPU?

Mistral Large 3 — frequently asked questions

How much VRAM does Mistral Large 3 need?

Mistral Large 3 needs about 408 GB VRAM at Q4_K_M quantization for its smallest variant. Variants: Mistral Large 3 675B-A41B (408 GB, Q4_K_M). On Apple Silicon, unified memory counts toward this requirement.

Can I run Mistral Large 3 on an RTX 4090 (24 GB)?

Mistral Large 3's smallest variant needs about 408 GB, which exceeds a single RTX 4090 (24 GB). Use multiple GPUs, a higher-VRAM card, or Apple Silicon with large unified memory.

What quantization should I use for Mistral Large 3?

Q4_K_M is the best balance of quality and VRAM for Mistral Large 3 in most cases. Choose Q8_0 for near-lossless quality if you have spare VRAM, or smaller quants (Q3/Q2) only when memory is tight.

How do I run Mistral Large 3 with Ollama?

Mistral Large 3 has no local Ollama tag — the published tag is cloud-hosted, so running it sends your prompts to a hosted GPU rather than your own machine.