Best Local LLMs for the AMD Ryzen AI Max+ PRO 495
Written by Jakub Rusinowski · Last updated November 11, 2026
Best all-round pick: Qwen 3 235B-A22B (MoE)
The AMD Ryzen AI Max+ PRO 495 has 192 GB of VRAM, of which about 192 GB is available to a model. The largest model it can hold is MiMo-V2.5 310B (310B, 188 GB at Q4_K_M).
Best models overall on the AMD Ryzen AI Max+ PRO 495
| Model | Score | Memory at Q4_K_M | Context | Licence |
|---|---|---|---|---|
| Qwen 3 235B-A22B (MoE) | 97 | 142.7 GB | 125K | Apache 2.0 |
| DeepSeek V4-Flash | 95.7 | 172.3 GB | 977K | MIT |
| MiniMax M2.5 230B | 94.2 | 139.6 GB | 977K | Modified MIT (attribution required) |
| MiniMax M3-VL | 93.8 | 139.7 GB | 977K | Modified MIT (attribution required) |
| GPT-OSS 120B | 93.2 | 71.3 GB | 128K | Apache-2.0 |
| MiMo-V2.5 310B | 92.9 | 188 GB | 977K | MIT |
Best model by what you are doing
| Workload | Recommended on this GPU |
|---|---|
| Coding | DeepSeek V4-Flash (99.2) MiniMax M2.5 230B (97.4) Devstral-2 123B (96.8) |
| General assistant | Qwen 3 235B-A22B (MoE) (97) DeepSeek V4-Flash (95.7) MiniMax M2.5 230B (94.2) |
| Reasoning | Qwen 3 235B-A22B (MoE) (100) DeepSeek V4-Flash (99) GLM-5.1 72B (97.4) |
| RAG | DeepSeek V4-Flash (98.8) MiniMax M2.5 230B (96.2) MiMo-V2.5 310B (95.9) |
| Agents | MiMo-V2.5 310B (95.9) Qwen3.8-Flash-Next (93.6) Devstral-2 123B (93.3) |
| Vision | MiniMax M3-VL (99.4) Qwen 3.5 72B (95.5) MiniMax M2.5 230B (93.9) |
How these numbers are calculated
- Usable memory is 192 GB of the card's 192 GB.
- Fit is measured at Q4_K_M — quantized weights plus KV cache plus 0.8 GB runtime overhead.
- Within this card's budget, models are ranked on how well they use the memory available, not on being small — so the recommendation scales with the hardware.
FAQ
What is the best LLM for the AMD Ryzen AI Max+ PRO 495?
Qwen 3 235B-A22B (MoE) is the strongest all-round pick that fits its 192 GB.
What is the largest model the AMD Ryzen AI Max+ PRO 495 can run?
MiMo-V2.5 310B — 310B parameters, needing 188 GB at Q4_K_M.
How much of the AMD Ryzen AI Max+ PRO 495's memory can a model actually use?
About 192 GB of its 192 GB, before the desktop and runtime overhead are accounted for.
By Workload
- Best local LLMs for coding
- Best local LLMs for general assistant
- Best local LLMs for reasoning
- Best local LLMs for rag