Can I Run Gemma 4 on NVIDIA GeForce RTX 4080?

Written by Jakub Rusinowski · Last updated July 12, 2026

Yes, comfortably — you'll have ~8.8 GB of headroom running Gemma 4 12B (Unified) at Q4_K_M (7.245 GB, ~71 tok/s (est.)) with room for up to 32K context.

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NVIDIA GeForce RTX 4080 16GB
16 GB VRAM · 320 W board power
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NVIDIA GeForce RTX 4080 Specs

VRAM16 GB
Memory Bandwidth717 GB/s

Gemma 4 12B (Unified) on the NVIDIA GeForce RTX 4080: VRAM by quantization

QuantVRAM neededFits 16 GB?Max context
F1625.5 GB✗ No
Q8_014.2 GB✓ Yes8K
Q6_K11.3 GB✓ Yes32K
Q5_K_M10 GB✓ Yes32K
Q4_K_M8.7 GB✓ Yes32K
Q3_K_M6.6 GB✓ Yes32K
Q2_K5.4 GB✓ Yes64K

VRAM needed assumes a 4K-token context with an f16 KV cache; “Max context” is the largest window that still fits in 16 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Gemma 4 Sizes That Fit the NVIDIA GeForce RTX 4080

Gemma 4 12B (Unified)Q4_K_M · 7.245 GB · ~71 tok/s (est.)
Gemma 4 E4BQ4 (QAT) · 4.5 GB · ~101 tok/s (est.)
Gemma 4 E2BQ4 (QAT) · 2.86875 GB · ~137 tok/s (est.)
Buy vs. rent Gemma 4
Buy the GPU
~$1,199
NVIDIA GeForce RTX 4080 · MSRP
Rent by the hour
from $0.34/hr
RTX 4090 (24 GB) class

At 2 hrs/day, buying (~$1,199) beats renting at $0.34/hr after about 4.9 years.

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RunPod $0.34/hr
Rent on RunPod →
Vast.ai $0.35/hr · typical low · varies
Rent on Vast.ai →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Will Gemma 4 run on the NVIDIA GeForce RTX 4080?

Yes, comfortably — you'll have ~8.8 GB of headroom running Gemma 4 12B (Unified) at Q4_K_M (7.245 GB, ~71 tok/s (est.)) with room for up to 32K context.

Which Gemma 4 variant fits best on the NVIDIA GeForce RTX 4080?

Gemma 4 12B (Unified) at Q4_K_M quantization (7.245 GB), estimated ~71 tokens/sec, up to 32K context.

Gemma 4 on Other GPUs

Popular Models on the NVIDIA GeForce RTX 4080

VRAM Tier

Troubleshooting

Buying Guide

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