Can I Run GPT-oss 120B on AMD Ryzen AI Max+ 395?

Written by Jakub Rusinowski · Last updated August 15, 2026

Yes. GPT-oss 120B needs 72.5 GB at Q4_K_M and the AMD Ryzen AI Max+ 395 has 96 GB, leaving about 23.5 GB of headroom, at roughly 2 tok/s (estimated) with room for up to 128K of context.

The numbers

ModelGPT-oss 120B
Parameters120B
QuantizationQ4_K_M
VRAM needed72.5 GB
AMD Ryzen AI Max+ 395 VRAM96 GB
VerdictRuns
Max context128K
Estimated speed~2 tok/s

What to do next

Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.

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Running GPT-oss 120B on this card:

Ryzen AI Max+ 395 Laptop (Strix Halo, up to 128GB)
96 GB VRAM · 120 W board power
2026 prices are volatile — check the current listing.
Check price on Amazon

Buy vs. rent GPT-oss 120B
Buy the GPU
~$1,999
AMD Ryzen AI Max+ 395 · MSRP
Rent by the hour
from $0.77/hr
A100 (80 GB) class

At 2 hrs/day, buying (~$1,999) beats renting at $0.77/hr after about 3.6 years.

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Vast.ai $0.77/hr · typical low · varies
Rent on Vast.ai →
RunPod $1.39/hr
Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other GPT-OSS sizes on the AMD Ryzen AI Max+ 395

GPT-oss 120B on nearby hardware

All GPT-OSS sizes on the AMD Ryzen AI Max+ 395 | VRAM calculator for GPT-oss 120B | AMD Ryzen AI Max+ 395 GPU page | Check your hardware