Can I Run GPT-OSS on NVIDIA H100 80GB?

Written by Jakub Rusinowski · Last updated August 15, 2026

Yes, but it's tight — GPT-oss 120B at Q4_K_M needs 72.45 GB of the NVIDIA H100 80GB's 80 GB, leaving only ~7.5 GB, ~22 tok/s (est.) with room for up to 64K context.

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NVIDIA H100 80GB PCIe
80 GB VRAM · 350 W board power
2026 prices are volatile — check the current listing.
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NVIDIA H100 80GB Specs

VRAM80 GB
Memory Bandwidth2000 GB/s

GPT-oss 120B on the NVIDIA H100 80GB: VRAM by quantization

QuantVRAM neededFits 80 GB?Max context
F16241.1 GB✗ No
Q8_0128.6 GB✗ No
Q6_K99.5 GB✗ No
Q5_K_M86.2 GB✗ No
Q4_K_M73.6 GB✓ Yes64K
Q3_K_M52.3 GB✓ Yes64K
Q2_K40.6 GB✓ Yes64K

VRAM needed assumes a 4K-token context with an f16 KV cache; “Max context” is the largest window that still fits in 80 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

GPT-OSS Sizes That Fit the NVIDIA H100 80GB

GPT-oss 120BQ4_K_M · 72.45 GB · ~22 tok/s (est.)
GPT-OSS 20BMXFP4 · 10.625 GB · ~116 tok/s (est.)
Buy vs. rent GPT-OSS
Buy the GPU
~$25,000
NVIDIA H100 80GB · MSRP
Rent by the hour
from $0.77/hr
A100 (80 GB) class

At 2 hrs/day, buying (~$25,000) beats renting at $0.77/hr after about 45.1 years.

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Vast.ai $0.77/hr · typical low · varies
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Is the NVIDIA H100 80GB enough to run GPT-OSS locally?

Yes, but it's tight — GPT-oss 120B at Q4_K_M needs 72.45 GB of the NVIDIA H100 80GB's 80 GB, leaving only ~7.5 GB, ~22 tok/s (est.) with room for up to 64K context.

What's the best GPT-OSS size for the NVIDIA H100 80GB?

GPT-oss 120B at Q4_K_M quantization (72.45 GB), estimated ~22 tokens/sec, up to 64K context.

GPT-OSS on Other GPUs

Popular Models on the NVIDIA H100 80GB

VRAM Tier

Troubleshooting

Buying Guide

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