Can I Run Llama 4.5 on AMD Ryzen AI Max+ 395?
Written by Jakub Rusinowski · Last updated July 12, 2026
Yes, comfortably — Llama 4.5 Scout at Q4_K_M needs 69.4 GB at 8K context (65.8 GB weights + 3.6 GB KV cache/overhead), leaving ~58.6 GB of the AMD Ryzen AI Max+ 395's 128 GB, at ~14 tok/s (est.), with room for up to 128K context.
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AMD Ryzen AI Max+ 395 Specs
| VRAM | 128 GB |
| Memory Bandwidth | 256 GB/s |
Llama 4.5 Scout on the AMD Ryzen AI Max+ 395: VRAM by quantization
| Quant | VRAM needed | Fits 128 GB? | Max context | Whole PC |
|---|---|---|---|---|
| F16 | 221.6 GB | ✗ No | — | — |
| Q8_0 | 119.4 GB | ✓ Yes | 32K | — |
| Q6_K | 92.9 GB | ✓ Yes | 64K | — |
| Q5_K_M | 80.8 GB | ✓ Yes | 128K | — |
| Q4_K_M | 69.4 GB | ✓ Yes | 128K | — |
| Q3_K_M | 50 GB | ✓ Yes | 128K | — |
| Q2_K | 39.4 GB | ✓ Yes | 256K | — |
Assumes an 8K-token context with an f16 KV cache, on an estimated architecture — this model publishes no config we can read. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 128 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.
Context costs VRAM too. At Q4_K_M on the AMD Ryzen AI Max+ 395: 8K 69.4 GB · 32K 77.6 GB · 128K 110.6 GB. Every window this model publishes still fits 128 GB.
No compatible GPU? Llama 4.5 Scout on 64 GB of system RAM, CPU only: runs, but it is tight.
Llama 4.5 Sizes That Fit the AMD Ryzen AI Max+ 395 (at 8K context)
| Llama 4.5 Scout | Q4_K_M · 69.4 GB at 8K context · ~14 tok/s (est.) |
Llama 4.5 needs ~69 GB but this GPU has 128 GB. Rent a A100 (80 GB)-class GPU by the hour instead of buying one:
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FAQ
Does the AMD Ryzen AI Max+ 395 have enough VRAM for Llama 4.5?
Yes, comfortably — Llama 4.5 Scout at Q4_K_M needs 69.4 GB at 8K context (65.8 GB weights + 3.6 GB KV cache/overhead), leaving ~58.6 GB of the AMD Ryzen AI Max+ 395's 128 GB, at ~14 tok/s (est.), with room for up to 128K context.
Which quantization of Llama 4.5 should I use on the AMD Ryzen AI Max+ 395?
Llama 4.5 Scout at Q4_K_M quantization needs 69.4 GB at 8K context (65.8 GB weights + 3.6 GB KV cache/overhead), estimated ~14 tokens/sec, up to 128K context.
Llama 4.5 on Other GPUs
- Llama 4.5 on Apple M4 Max
- Llama 4.5 on Apple M3 Max
- Llama 4.5 on Apple M1 Ultra
- Llama 4.5 on Apple M5 Max
- Llama 4.5 on NVIDIA DGX Spark
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← Can I Run It? | Llama 4.5 Model Page | AMD Ryzen AI Max+ 395 GPU Page | VRAM calculator | Check Your Hardware