Can I Run Qwen 2.5 Family on NVIDIA RTX 6000 Ada Generation?

Superseded model. Qwen 2.5 Family has been superseded by Qwen 3. This page is kept for reference; the newer family is a better starting point. View Qwen 3 →

Written by Jakub Rusinowski · Last updated July 21, 2026

Yes, but it's tight — Qwen 2.5 72B Instruct at Q4_K_M needs 43.47 GB of the NVIDIA RTX 6000 Ada Generation's 48 GB, leaving only ~4.5 GB, ~19 tok/s (est.) with room for up to 8K context.

Buy This HardwareNVIDIA RTX 6000 Ada Generation 48GB — 48 GB VRAM · 300 W board powerDeploy in the Cloud NowNVIDIA A40 on RunPod — from $0.44/hr · rate checked 2026-08

or compare on Vast.ai

As an Amazon Associate we earn from qualifying purchases. Cloud GPU links are referral links — we may earn a commission at no extra cost to you.

Affiliate disclosure: Some links on this page are affiliate links — if you buy through them, LLM Configurator may earn a commission at no extra cost to you. As an Amazon Associate, LLM Configurator earns from qualifying purchases.

NVIDIA RTX 6000 Ada Generation 48GB
48 GB VRAM · 300 W board power
2026 prices are volatile — check the current listing.
Check price on Amazon

NVIDIA RTX 6000 Ada Generation Specs

VRAM48 GB
Memory Bandwidth960 GB/s

Qwen 2.5 72B Instruct on the NVIDIA RTX 6000 Ada Generation: VRAM by quantization

QuantVRAM neededFits 48 GB?Max context
F16146.1 GB✗ No
Q8_078.6 GB✗ No
Q6_K61.2 GB✗ No
Q5_K_M53.2 GB✗ No
Q4_K_M45.6 GB✓ Yes8K
Q3_K_M32.8 GB✓ Yes32K
Q2_K25.8 GB✓ Yes64K

VRAM needed assumes a 4K-token context with an f16 KV cache; “Max context” is the largest window that still fits in 48 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Qwen 2.5 Family Sizes That Fit the NVIDIA RTX 6000 Ada Generation

Qwen 2.5 72B InstructQ4_K_M · 43.47 GB · ~19 tok/s (est.)
Qwen 2.5 Coder 32BQ4_K_M · 19.32 GB · ~40 tok/s (est.)
Qwen 2.5 14B InstructQ4_K_M · 8.4525 GB · ~79 tok/s (est.)
Qwen 2.5 7B InstructQ4_K_M · 4.5885 GB · ~130 tok/s (est.)
Buy vs. rent Qwen 2.5 Family
Buy the GPU
~$6,799
NVIDIA RTX 6000 Ada Generation · MSRP
Rent by the hour
from $0.77/hr
A100 (80 GB) class

At 2 hrs/day, buying (~$6,799) beats renting at $0.77/hr after about 12.3 years.

Affiliate links — we may earn a commission if you sign up, at no extra cost to you.

Vast.ai $0.77/hr · typical low · varies
Rent on Vast.ai →
RunPod $1.39/hr
Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Is the NVIDIA RTX 6000 Ada Generation enough to run Qwen 2.5 Family locally?

Yes, but it's tight — Qwen 2.5 72B Instruct at Q4_K_M needs 43.47 GB of the NVIDIA RTX 6000 Ada Generation's 48 GB, leaving only ~4.5 GB, ~19 tok/s (est.) with room for up to 8K context.

What's the best Qwen 2.5 Family size for the NVIDIA RTX 6000 Ada Generation?

Qwen 2.5 72B Instruct at Q4_K_M quantization (43.47 GB), estimated ~19 tokens/sec, up to 8K context.

Qwen 2.5 Family on Other GPUs

Popular Models on the NVIDIA RTX 6000 Ada Generation

VRAM Tier

Troubleshooting

Buying Guide

← Can I Run It? | Qwen 2.5 Family Model Page | NVIDIA RTX 6000 Ada Generation GPU Page | Check Your Hardware