Can I Run Qwen 3.5 27B on NVIDIA H100 80GB (PCIe)?
Written by Jakub Rusinowski · Last updated July 21, 2026
Yes. Qwen 3.5 27B needs 18.8 GB at 8K context (16.3 GB weights + 2.5 GB KV cache/overhead) at Q4_K_M and the NVIDIA H100 80GB (PCIe) has 80 GB, leaving about 61.2 GB of headroom, at roughly 81 tok/s (estimated) with room for up to 128K of context.
See what else this hardware can run →
The numbers
| Model | Qwen 3.5 27B |
| Parameters | 27B |
| Quantization | Q4_K_M |
| VRAM needed (8K context) | 18.8 GB |
| NVIDIA H100 80GB (PCIe) VRAM | 80 GB |
| Verdict | Runs |
| Max context | 128K |
| Estimated speed | ~81 tok/s |
Qwen 3.5 27B on the NVIDIA H100 80GB (PCIe): VRAM by quantization
| Quant | VRAM needed | Fits 80 GB? | Max context | Whole PC |
|---|---|---|---|---|
| F16 | 56.5 GB | ✓ Yes | 64K | — |
| Q8_0 | 31.2 GB | ✓ Yes | 128K | Build for this |
| Q6_K | 24.7 GB | ✓ Yes | 128K | — |
| Q5_K_M | 21.7 GB | ✓ Yes | 128K | — |
| Q4_K_M | 18.8 GB | ✓ Yes | 128K | Build for this |
| Q3_K_M | 14.1 GB | ✓ Yes | 128K | — |
| Q2_K | 11.4 GB | ✓ Yes | 128K | — |
Assumes an 8K-token context with an f16 KV cache, on an estimated architecture — this model publishes no config we can read. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 80 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.
Context costs VRAM too. At Q4_K_M on the NVIDIA H100 80GB (PCIe): 8K 18.8 GB · 32K 24.1 GB · 128K 45 GB. Every window this model publishes still fits 80 GB.
What to do next
Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.
No compatible GPU? Qwen 3.5 27B on 24 GB of system RAM, CPU only: runs comfortably.
Running Qwen 3.5 27B on this card:
At 2 hrs/day, buying (~$25,000) beats renting at $0.34/hr after about 102.1 years.
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.
Other Qwen 3.5 sizes on the NVIDIA H100 80GB (PCIe)
- Qwen 3.5 397B-A17B — does not fit (139 GB)
- Qwen 3.5 122B-A10B — runs (77.3 GB)
- Qwen 3.5 35B-A3B — runs (23.8 GB)
- Qwen 3.5 9B — runs (6.5 GB)
- Qwen 3.5 4B — runs (3.5 GB)
- Qwen 3.5 2B — runs (2.7 GB)
- Qwen 3.5 0.8B — runs (1.8 GB)
Qwen 3.5 27B on nearby hardware
- NVIDIA L40S (48 GB) — runs
- NVIDIA RTX PRO 6000 Blackwell (96 GB) — runs
All Qwen 3.5 sizes on the NVIDIA H100 80GB (PCIe) | Qwen 3.5 27B model page | NVIDIA H100 80GB (PCIe) GPU page | VRAM calculator | Check your hardware