Can I Run Qwen 3.5 on NVIDIA H100 80GB?

Written by Jakub Rusinowski · Last updated July 21, 2026

Yes, but it's tight — Qwen 3.5 122B-A10B at Q4_K_M needs 73.6575 GB of the NVIDIA H100 80GB's 80 GB, leaving only ~6.3 GB, ~151 tok/s (est.) with room for up to 8K context.

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NVIDIA H100 80GB PCIe
Launch MSRP: $25,000
2026 prices are volatile — check the current listing.
Check price on Amazon

NVIDIA H100 80GB Specs

VRAM80 GB
Memory Bandwidth2000 GB/s

Qwen 3.5 122B-A10B on the NVIDIA H100 80GB: VRAM by quantization

QuantVRAM neededFits 80 GB?Max context
F16246.2 GB✗ No
Q8_0131.9 GB✗ No
Q6_K102.3 GB✗ No
Q5_K_M88.7 GB✗ No
Q4_K_M75.9 GB✓ Yes8K
Q3_K_M54.2 GB✓ Yes64K
Q2_K42.3 GB✓ Yes64K

VRAM needed assumes a 4K-token context with an f16 KV cache; “Max context” is the largest window that still fits in 80 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Qwen 3.5 Sizes That Fit the NVIDIA H100 80GB

Qwen 3.5 122B-A10BQ4_K_M · 73.6575 GB · ~151 tok/s (est.)
Qwen 3.5 35B-A3BQ4_K_M · 21.13125 GB · ~259 tok/s (est.)
Qwen 3.5 27BQ4_K_M · 16.30125 GB · ~81 tok/s (est.)
Qwen 3.5 9BQ4_K_M · 5.43375 GB · ~172 tok/s (est.)
Qwen 3.5 4BQ4_K_M · 2.415 GB · ~254 tok/s (est.)
Qwen 3.5 2BQ4_K_M · 1.2075 GB · ~315 tok/s (est.)
Qwen 3.5 0.8BQ4_K_M · 0.48300000000000004 GB · ~372 tok/s (est.)
Buy vs. rent Qwen 3.5
Buy the GPU
~$25,000
NVIDIA H100 80GB · MSRP
Rent by the hour
from $0.77/hr
A100 (80 GB) class

At 2 hrs/day, buying (~$25,000) beats renting at $0.77/hr after about 45.1 years.

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Vast.ai $0.77/hr · typical low · varies
Rent on Vast.ai →
RunPod $1.39/hr
Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Is the NVIDIA H100 80GB enough to run Qwen 3.5 locally?

Yes, but it's tight — Qwen 3.5 122B-A10B at Q4_K_M needs 73.6575 GB of the NVIDIA H100 80GB's 80 GB, leaving only ~6.3 GB, ~151 tok/s (est.) with room for up to 8K context.

What's the best Qwen 3.5 size for the NVIDIA H100 80GB?

Qwen 3.5 122B-A10B at Q4_K_M quantization (73.6575 GB), estimated ~151 tokens/sec, up to 8K context.

Qwen 3.5 on Other GPUs

Popular Models on the NVIDIA H100 80GB

VRAM Tier

Troubleshooting

Buying Guide

← Can I Run It? | Qwen 3.5 Model Page | NVIDIA H100 80GB GPU Page | Check Your Hardware