Can I Run Qwen 3.5 on NVIDIA H100 80GB (PCIe)?

Written by Jakub Rusinowski · Last updated July 21, 2026

Yes, but it's tight — Qwen 3.5 122B-A10B at Q4_K_M needs 77.3 GB at 8K context (73.7 GB weights + 3.6 GB KV cache/overhead), leaving ~2.7 GB of the NVIDIA H100 80GB (PCIe)'s 80 GB, at ~151 tok/s (est.), with room for up to 8K context.

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NVIDIA H100 80GB PCIe
80 GB VRAM · 350 W board power
2026 prices are volatile — check the current listing.
Check price on Amazon

NVIDIA H100 80GB (PCIe) Specs

VRAM80 GB
Memory Bandwidth2000 GB/s

Qwen 3.5 122B-A10B on the NVIDIA H100 80GB (PCIe): VRAM by quantization

QuantVRAM neededFits 80 GB?Max contextWhole PC
F16247.7 GB✗ No——
Q8_0133.3 GB✗ No——
Q6_K103.7 GB✗ No——
Q5_K_M90.1 GB✗ No——
Q4_K_M77.3 GB✓ Yes8K—
Q3_K_M55.7 GB✓ Yes64K—
Q2_K43.8 GB✓ Yes64K—

Assumes an 8K-token context with an f16 KV cache, on an estimated architecture — this model publishes no config we can read. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 80 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Context costs VRAM too. At Q4_K_M on the NVIDIA H100 80GB (PCIe): 8K 77.3 GB · 32K 85.9 GB ✗ · 128K 120.1 GB ✗. Past 32K it no longer fits 80 GB — a q8_0 KV cache buys roughly half of that back, which the calculator will price for you.

No compatible GPU? Qwen 3.5 122B-A10B on 128 GB of system RAM, CPU only: runs.

Qwen 3.5 Sizes That Fit the NVIDIA H100 80GB (PCIe) (at 8K context)

Qwen 3.5 122B-A10BQ4_K_M · 77.3 GB at 8K context · ~151 tok/s (est.)
Qwen 3.5 35B-A3BQ4_K_M · 23.8 GB at 8K context · ~259 tok/s (est.)
Qwen 3.5 27BQ4_K_M · 18.8 GB at 8K context · ~81 tok/s (est.)
Qwen 3.5 9BQ4_K_M · 6.5 GB at 8K context · ~181 tok/s (est.)
Qwen 3.5 4BQ4_K_M · 3.5 GB at 8K context · ~267 tok/s (est.)
Qwen 3.5 2BQ4_K_M · 2.7 GB at 8K context · ~315 tok/s (est.)
Qwen 3.5 0.8BQ4_K_M · 1.8 GB at 8K context · ~372 tok/s (est.)
Buy vs. rent Qwen 3.5
Buy the GPU
~$25,000
NVIDIA H100 80GB (PCIe) · MSRP
Rent by the hour
from $0.77/hr
A100 (80 GB) class

At 2 hrs/day, buying (~$25,000) beats renting at $0.77/hr after about 45.1 years.

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Vast.ai $0.77/hr · typical low · varies
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Is the NVIDIA H100 80GB (PCIe) enough to run Qwen 3.5 locally?

Yes, but it's tight — Qwen 3.5 122B-A10B at Q4_K_M needs 77.3 GB at 8K context (73.7 GB weights + 3.6 GB KV cache/overhead), leaving ~2.7 GB of the NVIDIA H100 80GB (PCIe)'s 80 GB, at ~151 tok/s (est.), with room for up to 8K context.

What's the best Qwen 3.5 size for the NVIDIA H100 80GB (PCIe)?

Qwen 3.5 122B-A10B at Q4_K_M quantization needs 77.3 GB at 8K context (73.7 GB weights + 3.6 GB KV cache/overhead), estimated ~151 tokens/sec, up to 8K context.

Every Qwen 3.5 size on the NVIDIA H100 80GB (PCIe)

SizeVRAM at 8KVerdictSpeed
Qwen 3.5 397B-A17B139 GBDoes not fit—
Qwen 3.5 122B-A10B77.3 GBRuns~151 tok/s
Qwen 3.5 35B-A3B23.8 GBRuns~259 tok/s
Qwen 3.5 27B18.8 GBRuns~81 tok/s
Qwen 3.5 9B6.5 GBRuns~181 tok/s
Qwen 3.5 4B3.5 GBRuns~267 tok/s
Qwen 3.5 2B2.7 GBRuns~315 tok/s
Qwen 3.5 0.8B1.8 GBRuns~372 tok/s

Qwen 3.5 on Other GPUs

Popular Models on the NVIDIA H100 80GB (PCIe)

VRAM Tier

Troubleshooting

Buying Guide

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