Can I Run Gemma 4 12B (Unified) on NVIDIA GeForce RTX 5080?

作者: Jakub Rusinowski · 最后更新: 2026年9月29日

Yes. Gemma 4 12B (Unified) needs 8.7 GB at 8K context (7.2 GB weights + 1.5 GB KV cache/overhead) at Q4_K_M and the NVIDIA GeForce RTX 5080 has 16 GB, leaving about 7.3 GB of headroom, at roughly 85 tok/s (estimated) with room for up to 64K of context.

See what else this hardware can run →

The numbers

ModelGemma 4 12B (Unified)
Parameters12B
QuantizationQ4_K_M
VRAM needed (8K context)8.7 GB
NVIDIA GeForce RTX 5080 VRAM16 GB
VerdictRuns
Max context64K
Estimated speed~85 tok/s

Gemma 4 12B (Unified) on the NVIDIA GeForce RTX 5080: VRAM by quantization

QuantVRAM neededFits 16 GB?Max contextWhole PC
F1625.4 GB✗ No——
Q8_014.2 GB✓ Yes64K—
Q6_K11.3 GB✓ Yes64K—
Q5_K_M9.9 GB✓ Yes64K—
Q4_K_M8.7 GB✓ Yes64K—
Q3_K_M6.6 GB✓ Yes64K—
Q2_K5.4 GB✓ Yes64K—

Assumes an 8K-token context with an f16 KV cache. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 16 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Context costs VRAM too. At Q4_K_M on the NVIDIA GeForce RTX 5080: 8K 8.7 GB · 32K 9.1 GB · 125K 10.6 GB. Every window this model publishes still fits 16 GB.

What to do next

Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.

No compatible GPU? Gemma 4 12B (Unified) on 16 GB of system RAM, CPU only: runs.

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Running Gemma 4 12B (Unified) on this card:

NVIDIA GeForce RTX 5080 16GB
16 GB VRAM · 360 W board power
2026年价格波动较大——请以当前商品页价格为准。
在亚马逊查看价格

Buy vs. rent Gemma 4 12B (Unified)
Buy the GPU
~$999
NVIDIA GeForce RTX 5080 · MSRP
Rent by the hour
from $0.34/hr
RTX 4090 (24 GB) class

At 2 hrs/day, buying (~$999) beats renting at $0.34/hr after about 4.1 years.

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RunPod $0.34/hr
Rent on RunPod →
Vast.ai $0.35/hr · typical low · varies
Rent on Vast.ai →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Gemma 4 sizes on the NVIDIA GeForce RTX 5080

Gemma 4 12B (Unified) on nearby hardware

All Gemma 4 sizes on the NVIDIA GeForce RTX 5080 | Gemma 4 12B (Unified) model page | NVIDIA GeForce RTX 5080 GPU page | VRAM calculator | Check your hardware