Can I Run Qwen 2.5 14B Instruct on NVIDIA L40S?

Name: LLM Configurator — GPU VRAM Checker
Author: LLM Configurator

作者： Jakub Rusinowski · 最后更新： 2026年8月15日

Yes. Qwen 2.5 14B Instruct needs 8.5 GB at Q4_K_M and the NVIDIA L40S has 48 GB, leaving about 39.5 GB of headroom, at roughly 72 tok/s (estimated) with room for up to 128K of context.

The numbers

Model	Qwen 2.5 14B Instruct
Parameters	14B
Quantization	Q4_K_M
VRAM needed	8.5 GB
NVIDIA L40S VRAM	48 GB
Verdict	Runs
Max context	128K
Estimated speed	~72 tok/s

What to do next

Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.

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Running Qwen 2.5 14B Instruct on this card:

NVIDIA L40S 48GB

48 GB VRAM · 350 W board power

2026年价格波动较大——请以当前商品页价格为准。

在亚马逊查看价格

Buy vs. rent Qwen 2.5 14B Instruct

Buy the GPU

~$7,499

NVIDIA L40S · MSRP

Rent by the hour

from $0.34/hr

RTX 4090 (24 GB) class

At 2 hrs/day, buying (~$7,499) beats renting at $0.34/hr after about 30.6 years.

Affiliate links — we may earn a commission if you sign up, at no extra cost to you.

RunPod $0.34/hr

Rent on RunPod →

Vast.ai $0.35/hr · typical low · varies

Rent on Vast.ai →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Qwen 2.5 Family sizes on the NVIDIA L40S

Qwen 2.5 72B Instruct — runs (43.5 GB)
Qwen 2.5 Coder 32B — runs (19.3 GB)
Qwen 2.5 7B Instruct — runs (4.6 GB)

Qwen 2.5 14B Instruct on nearby hardware

Apple M3 Pro (36 GB) — runs
Apple M3 Max (64 GB) — runs

All Qwen 2.5 Family sizes on the NVIDIA L40S | VRAM calculator for Qwen 2.5 14B Instruct | NVIDIA L40S GPU page | Check your hardware