Can I Run Qwen 2.5 Family on AMD Ryzen AI Max+ 395?

Name: LLM Configurator — GPU VRAM Checker
Author: LLM Configurator

Superseded model. Qwen 2.5 Family has been superseded by Qwen 3. This page is kept for reference; the newer family is a better starting point. View Qwen 3 →

作者： Jakub Rusinowski · 最后更新： 2026年7月12日

Yes, comfortably — you'll have ~52.5 GB of headroom running Qwen 2.5 72B Instruct at Q4_K_M (43.47 GB, ~4 tok/s (est.)) with room for up to 128K context.

Buy This HardwareRyzen AI Max+ 395 Laptop (Strix Halo, up to 128GB) — 96 GB VRAM · 120 W board power Deploy in the Cloud NowNVIDIA A40 on RunPod — from $0.44/hr · rate checked 2026-08

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Ryzen AI Max+ 395 Laptop (Strix Halo, up to 128GB)

96 GB VRAM · 120 W board power

2026年价格波动较大——请以当前商品页价格为准。

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AMD Ryzen AI Max+ 395 Specs

VRAM	96 GB
Memory Bandwidth	256 GB/s

Qwen 2.5 72B Instruct on the AMD Ryzen AI Max+ 395: VRAM by quantization

Quant	VRAM needed	Fits 96 GB?	Max context
F16	146.1 GB	✗ No	—
Q8_0	78.6 GB	✓ Yes	32K
Q6_K	61.2 GB	✓ Yes	64K
Q5_K_M	53.2 GB	✓ Yes	128K
Q4_K_M	45.6 GB	✓ Yes	128K
Q3_K_M	32.8 GB	✓ Yes	128K
Q2_K	25.8 GB	✓ Yes	128K

VRAM needed assumes a 4K-token context with an f16 KV cache; “Max context” is the largest window that still fits in 96 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.

Qwen 2.5 Family Sizes That Fit the AMD Ryzen AI Max+ 395

Qwen 2.5 72B Instruct	Q4_K_M · 43.47 GB · ~4 tok/s (est.)
Qwen 2.5 Coder 32B	Q4_K_M · 19.32 GB · ~8 tok/s (est.)
Qwen 2.5 14B Instruct	Q4_K_M · 8.4525 GB · ~17 tok/s (est.)
Qwen 2.5 7B Instruct	Q4_K_M · 4.5885 GB · ~31 tok/s (est.)

Buy vs. rent Qwen 2.5 Family

Buy the GPU

~$1,999

AMD Ryzen AI Max+ 395 · MSRP

Rent by the hour

from $0.77/hr

A100 (80 GB) class

At 2 hrs/day, buying (~$1,999) beats renting at $0.77/hr after about 3.6 years.

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Vast.ai $0.77/hr · typical low · varies

Rent on Vast.ai →

RunPod $1.39/hr

Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

FAQ

Qwen 2.5 Family on the AMD Ryzen AI Max+ 395 — does it fit?

Yes, comfortably — you'll have ~52.5 GB of headroom running Qwen 2.5 72B Instruct at Q4_K_M (43.47 GB, ~4 tok/s (est.)) with room for up to 128K context.

Which Qwen 2.5 Family variant fits best on the AMD Ryzen AI Max+ 395?

Qwen 2.5 72B Instruct at Q4_K_M quantization (43.47 GB), estimated ~4 tokens/sec, up to 128K context.

Every Qwen 2.5 Family size on the AMD Ryzen AI Max+ 395

Size	VRAM	Verdict	Speed
Qwen 2.5 72B Instruct	43.5 GB	Runs	~4 tok/s
Qwen 2.5 Coder 32B	19.3 GB	Runs	~8 tok/s
Qwen 2.5 14B Instruct	8.5 GB	Runs	~17 tok/s
Qwen 2.5 7B Instruct	4.6 GB	Runs	~31 tok/s

Qwen 2.5 Family on Other GPUs

Popular Models on the AMD Ryzen AI Max+ 395

VRAM Tier

Best LLMs for 80 GB VRAM

Troubleshooting

Which GGUF quant should I download? (Q4 vs Q5 vs Q8)

Buying Guide

Best GPU Buyer Guide 2026

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