Can I Run Qwen 2.5 VL 72B Instruct on Apple M5 Pro?

Name: LLM Configurator — GPU VRAM Checker
Author: LLM Configurator

作者： Jakub Rusinowski · 最后更新： 2026年8月15日

Yes. Qwen 2.5 VL 72B Instruct needs 44.3 GB at Q4_K_M and the Apple M5 Pro has 64 GB, leaving about 19.7 GB of headroom, at roughly 4 tok/s (estimated) with room for up to 32K of context.

The numbers

Model	Qwen 2.5 VL 72B Instruct
Parameters	72B
Quantization	Q4_K_M
VRAM needed	44.3 GB
Apple M5 Pro VRAM	64 GB
Verdict	Runs
Max context	32K
Estimated speed	~4 tok/s

What to do next

Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.

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Running Qwen 2.5 VL 72B Instruct on this card:

Apple MacBook Pro M5 Pro

64 GB VRAM · 30 W board power

2026年价格波动较大——请以当前商品页价格为准。

在亚马逊查看价格

Buy vs. rent Qwen 2.5 VL 72B Instruct

Buy the GPU

~$1,999

Apple M5 Pro · MSRP

Rent by the hour

from $0.77/hr

A100 (80 GB) class

At 2 hrs/day, buying (~$1,999) beats renting at $0.77/hr after about 3.6 years.

Affiliate links — we may earn a commission if you sign up, at no extra cost to you.

Vast.ai $0.77/hr · typical low · varies

Rent on Vast.ai →

RunPod $1.39/hr

Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Qwen 2.5 VL sizes on the Apple M5 Pro

Qwen 2.5 VL 7B Instruct — runs (5.0 GB)

Qwen 2.5 VL 72B Instruct on nearby hardware

NVIDIA L40S (48 GB) — runs
NVIDIA A100 80GB (80 GB) — runs

All Qwen 2.5 VL sizes on the Apple M5 Pro | VRAM calculator for Qwen 2.5 VL 72B Instruct | Apple M5 Pro GPU page | Check your hardware