Can I Run Gemma 3 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Written by Jakub Rusinowski · Last updated March 12, 2025

Yes — comfortably

Yes, comfortably — Gemma 3 27B Instruct at Q8_0 needs about 37.8 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB), leaving ~90.2 GB spare and running at ~5.8 tok/s (estimated), with room for about 65,536 tokens of context.

Confidence: high · Recommended quantization: Q8_0 · Estimated speed: ~5.8 tok/s

Framework Desktop (Ryzen AI Max+ 395, 128 GB) — what it gives a model

Usable memory for models128 GB
Memory bandwidth256 GB/s
Form factorMini PC
Operating systemWindows or Linux
Memory upgradeableNo — soldered

Gemma 3 on Framework Desktop (Ryzen AI Max+ 395, 128 GB): memory by quantization

QuantMemory neededFits 128 GB?Max contextEst. speedDownload
F1663.1 GB✓ Yes64K~3.3 tok/s54 GB
Q8_037.8 GB✓ Yes64K~5.8 tok/s28.7 GB
Q6_K31.3 GB✓ Yes64K~7.2 tok/s22.1 GB
Q5_K_M28.3 GB✓ Yes64K~8.1 tok/s19.1 GB
Q4_K_M25.4 GB✓ Yes64K~9.2 tok/s16.3 GB
Q3_K_M20.6 GB✓ Yes64K~11.9 tok/s11.5 GB
Q2_K18 GB✓ Yes64K~14.3 tok/s8.9 GB

Which Gemma 3 sizes fit

VariantNeeds at Q4_K_MFits?Est. speed
Gemma 3 27B Instruct25.4 GB✓ Fits~9.2 tok/s
Gemma 3 12B Instruct11.1 GB✓ Fits~20.8 tok/s
Gemma 3 4B Instruct4.4 GB✓ Fits~56.2 tok/s
Gemma 3 1B Instruct2 GB✓ Fits~143.6 tok/s

What to watch out for

Framework Desktop 128 GB limitations

Recommended setup

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

How these numbers are calculated

FAQ

Can I run Gemma 3 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Yes, comfortably — Gemma 3 27B Instruct at Q8_0 needs about 37.8 GB of the 128 GB usable on Framework Desktop (Ryzen AI Max+ 395, 128 GB), leaving ~90.2 GB spare and running at ~5.8 tok/s (estimated), with room for about 65,536 tokens of context.

Which quantization of Gemma 3 should I use on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Q8_0 — it needs about 37.8 GB of the 128 GB available, downloads as roughly 28.7 GB, and runs at an estimated 5.8 tokens/sec with up to 64K of context.

What limits Gemma 3 on Framework Desktop (Ryzen AI Max+ 395, 128 GB)?

Nothing binding — the model fits with headroom and generates at a usable speed on this hardware.

Which runtime should I use?

Ollama or llama.cpp (CUDA/ROCm) — vLLM if you need concurrent serving

Other Computers

Other Models on Framework Desktop (Ryzen AI Max+ 395, 128 GB)

Gemma 3 on GPUs

What This Model Is Good At

Model & Tools

← Can I Run It? | Gemma 3 model page | Check your hardware