Can I Run Qwen 3.5 122B-A10B on NVIDIA H100 80GB (PCIe)?
Autor: Jakub Rusinowski · Ostatnia aktualizacja: 21 lipca 2026
Yes, but it's tight. Qwen 3.5 122B-A10B needs 77.3 GB at 8K context (73.7 GB weights + 3.6 GB KV cache/overhead) at Q4_K_M and the NVIDIA H100 80GB (PCIe) has 80 GB, leaving about 2.7 GB of headroom, at roughly 151 tok/s (estimated) with room for up to 8K of context.
See what else this hardware can run →
The numbers
| Model | Qwen 3.5 122B-A10B |
| Parameters | 122B (10B active) |
| Quantization | Q4_K_M |
| VRAM needed (8K context) | 77.3 GB |
| NVIDIA H100 80GB (PCIe) VRAM | 80 GB |
| Verdict | Runs |
| Max context | 8K |
| Estimated speed | ~151 tok/s |
Qwen 3.5 122B-A10B on the NVIDIA H100 80GB (PCIe): VRAM by quantization
| Quant | VRAM needed | Fits 80 GB? | Max context | Whole PC |
|---|---|---|---|---|
| F16 | 247.7 GB | ✗ No | — | — |
| Q8_0 | 133.3 GB | ✗ No | — | — |
| Q6_K | 103.7 GB | ✗ No | — | — |
| Q5_K_M | 90.1 GB | ✗ No | — | — |
| Q4_K_M | 77.3 GB | ✓ Yes | 8K | — |
| Q3_K_M | 55.7 GB | ✓ Yes | 64K | — |
| Q2_K | 43.8 GB | ✓ Yes | 64K | — |
Assumes an 8K-token context with an f16 KV cache, on an estimated architecture — this model publishes no config we can read. A longer window needs more; a quantized KV cache needs less. “Max context” is the largest window that still fits in 80 GB. Figures are estimates from parameter count, quantization and memory bandwidth — the analyzer lets you tune KV-cache quant and context.
Context costs VRAM too. At Q4_K_M on the NVIDIA H100 80GB (PCIe): 8K 77.3 GB · 32K 85.9 GB ✗ · 128K 120.1 GB ✗. Past 32K it no longer fits 80 GB — a q8_0 KV cache buys roughly half of that back, which the calculator will price for you.
What to do next
Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.
No compatible GPU? Qwen 3.5 122B-A10B on 128 GB of system RAM, CPU only: runs.
Running Qwen 3.5 122B-A10B on this card:
At 2 hrs/day, buying (~$25,000) beats renting at $0.77/hr after about 45.1 years.
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Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.
Other Qwen 3.5 sizes on the NVIDIA H100 80GB (PCIe)
- Qwen 3.5 397B-A17B — does not fit (139 GB)
- Qwen 3.5 35B-A3B — runs (23.8 GB)
- Qwen 3.5 27B — runs (18.8 GB)
- Qwen 3.5 9B — runs (6.5 GB)
- Qwen 3.5 4B — runs (3.5 GB)
- Qwen 3.5 2B — runs (2.7 GB)
- Qwen 3.5 0.8B — runs (1.8 GB)
Qwen 3.5 122B-A10B on nearby hardware
- NVIDIA L40S (48 GB) — runs at a lower quant
- NVIDIA RTX PRO 6000 Blackwell (96 GB) — runs
All Qwen 3.5 sizes on the NVIDIA H100 80GB (PCIe) | Qwen 3.5 122B-A10B model page | NVIDIA H100 80GB (PCIe) GPU page | VRAM calculator | Check your hardware