Can I Run Qwen 2.5 72B Instruct on Apple M3 Pro?

作者: Jakub Rusinowski · 最后更新: 2026年8月15日

Not at Q4_K_M — that needs 43.5 GB and the Apple M3 Pro has 36 GB. Drop to Q3_K_M and it fits in 34.2 GB, with up to 8K of context.

The numbers

ModelQwen 2.5 72B Instruct
Parameters72B
QuantizationQ4_K_M
VRAM needed43.5 GB
Apple M3 Pro VRAM36 GB
VerdictRuns at a lower quant
Fits atQ3_K_M (34.2 GB)
Max context8K

What to do next

Quantize to Q3_K_M. That is the cheapest fix — it costs some quality but no money.

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Running Qwen 2.5 72B Instruct on this card:

Apple MacBook Pro M3 Pro
36 GB VRAM · 30 W board power
2026年价格波动较大——请以当前商品页价格为准。
在亚马逊查看价格

Won't fit — rent Qwen 2.5 72B Instruct instead

Qwen 2.5 72B Instruct needs ~43 GB but this GPU has 36 GB. Rent a A100 (80 GB)-class GPU by the hour instead of buying one:

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Vast.ai $0.77/hr · typical low · varies
Rent on Vast.ai →
RunPod $1.39/hr
Rent on RunPod →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Qwen 2.5 Family sizes on the Apple M3 Pro

Qwen 2.5 72B Instruct on nearby hardware

All Qwen 2.5 Family sizes on the Apple M3 Pro | VRAM calculator for Qwen 2.5 72B Instruct | Apple M3 Pro GPU page | Check your hardware