Can I Run Mistral NeMo 12B on NVIDIA GeForce RTX 5080?

Autor: Jakub Rusinowski · Ostatnia aktualizacja: 15 sierpnia 2026

Yes. Mistral NeMo 12B needs 7.2 GB at Q4_K_M and the NVIDIA GeForce RTX 5080 has 16 GB, leaving about 8.8 GB of headroom, at roughly 84 tok/s (estimated) with room for up to 32K of context.

The numbers

ModelMistral NeMo 12B
Parameters12B
QuantizationQ4_K_M
VRAM needed7.2 GB
NVIDIA GeForce RTX 5080 VRAM16 GB
VerdictRuns
Max context32K
Estimated speed~84 tok/s

What to do next

Nothing to change — run it at Q4_K_M. If you want more capability, check whether the next size up also fits.

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Running Mistral NeMo 12B on this card:

NVIDIA GeForce RTX 5080 16GB
16 GB VRAM · 360 W board power
Ceny w 2026 są niestabilne — sprawdź aktualną ofertę.
Sprawdź cenę na Amazon

Buy vs. rent Mistral NeMo 12B
Buy the GPU
~$999
NVIDIA GeForce RTX 5080 · MSRP
Rent by the hour
from $0.34/hr
RTX 4090 (24 GB) class

At 2 hrs/day, buying (~$999) beats renting at $0.34/hr after about 4.1 years.

Affiliate links — we may earn a commission if you sign up, at no extra cost to you.

RunPod $0.34/hr
Rent on RunPod →
Vast.ai $0.35/hr · typical low · varies
Rent on Vast.ai →

Cloud rates verified 2026-07 — estimates, and marketplace prices vary. Buying price is GPU MSRP only, not a full PC.

Other Mistral Family sizes on the NVIDIA GeForce RTX 5080

Mistral NeMo 12B on nearby hardware

All Mistral Family sizes on the NVIDIA GeForce RTX 5080 | VRAM calculator for Mistral NeMo 12B | NVIDIA GeForce RTX 5080 GPU page | Check your hardware